Sean Tomlin

Sean Tomlin

PhD in Biostatistics

The Ohio State University

Biography

I received my PhD in Biostatistics in August 2025 from the Interdisciplinary PhD Program in Biostatistics in the Department of Statistics and the Division of Biostatistics at The Ohio State University. My research interests include topics in causal inference, such as the use of matching, weighting, and regression methods in complex and multilevel observational studies, especially in designs with repeated measures. I also bring expertise in randomized clinical trials and aim to advance the rigorous application of causal inference in real-world evidence studies, both in regulatory science and clinical research. Currently, I am a Biostatistician at Medpace working on the design and analysis of clinical trials.

My dissertation, “Estimating Causal Effects from Observational Data in Quasi-Experimental Designs”, focused on modern problems in quasi-experimental causal inference, especially in difference-in-differences (DiD) designs employed in healthcare utilization studies. This includes addressing the controversial practice of matching on pre-intervention outcomes, and issues of structural zeros in DiD designs. I have also worked on formalizing limitations of retrospective survey data for causal inference, as we have many data constraints (e.g., omission of confounders) that arise from its secondary usage for causal questions, and sensitivity analysis that accounts for variation from survey sample design. Overall, this work not only clarifies some misconceptions in causal analysis with quasi-experiments but also provides powerful tools for practitioners to address common problems in health policy evaluation.

Interests
  • Causal inference
  • Constrained optimization
  • Quasi-experimental designs
  • Difference-in-differences
  • Survey methods
  • Health services research
  • Comparative effectiveness research
Education
  • PhD in Biostatistics, 2025

    The Ohio State University

  • MS in Statistics, 2022

    The Ohio State University

  • BS in Statistics, 2020

    Wright State University

  • 420 Cockins Hall, 1958 Neil Avenue, Columbus, OH 43210